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How the FDA tests plastic chemicals for safety

The FDA tests plastic chemicals for use in microwave ovens carefully because it knows some substances used in manufacturing plastics can, at high temperatures, diffuse out of the plastic into contained food.  These substances, called plasticizers, can harm humans.  Hence the care. 

The tiny plasticizer molecules move around in the plastic due to their thermal energy.  In fact, plasticizer molecules have such small molecular weights that the heated molecules can bop out of the plastic into contained food, much like water molecules leave a boiling pot of water and enter the air above the pot.  The higher the the plasticizer's temperature, the faster the molecules move.  This random thermal movement is called diffusion.

The FDA tests chemicals used to manufacture various plastic containers to make sure the amount of plasticizers that diffuses into the food is less than a maximum allowable amount.   The maximum allowable diffusion for a microwave-safe container or plastic wrap is 100 to 1000 times less per pound of body weight than the amount shown to harm laboratory animals over a life time of use. 

Container manufacturers then use only chemicals that the FDA authorizes for a "specific type of use and under specific conditions of use (time temperature)," emails Edward J. Machuga of  the FDA Office of Food Additive Safety.  These chemicals have passed the maximum-allowable-diffusion tests, and manufacturers can therefore label containers or wraps using such plastics as "microwave safe" on the manufacturer's container box.

The FDA tests include such steps as estimating:

  • the ratio of plastic surface area to food
  • how long the container will be in the microwave
  • how often a person will eat from the container
  • how hot the container might get during microwave heating

Further Reading:

Guidance for Industry: Microwave-only containers, FDA, April 2002; December 2007

(Answered 11 Jan. 2010)

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